Representative Publications

Journal Articles: * corresponding author

1. Chen, J, Wang, ZC, and Li, M* (accepted): Multiple “hits” during postnatal and early adulthood periods disrupt the normal development of sensorimotor gating ability in rats. Journal of Psychopharmacology.

2. Zhao, CJ, Li, M* (2009): The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: A double dissociation between dopamine D2 and 5-HT2A/2C receptors. Pharmacology, Biochemistry and Behavior, 2009 Oct;93(4):433-42. Epub 2009 Jun 17.

3. Li, M*, He, W, Mead, A (2009) An investigation of the behavioral mechanisms of antipsychotic action using a drug-drug conditioning paradigm. Behavioural Pharmacology, 2009 Mar;20(2):184-94.

4. Mead A, Li, M* (2009) Avoidance-Suppressing Effect of Antipsychotic Drugs is Progressively Potentiated after Repeated Administration: an Interoceptive Drug State Mechanism. Journal of Psychopharmacology, 2009 Mar 27. [Epub ahead of print]

5. Li, M*, Mead, A, Bevins, RA (2009) Individual Differences in Responding to Nicotine: Tracking Changes from Adolescence to Adulthood. Acta Pharmacol Sin 2009, Jun; 30 (6): 868–878

6. Li, M*, He W, Mead A (2009) Olanzapine and risperidone disrupt conditioned avoidance responding in phencyclidine or amphetamine pretreated rats by selectively weakening motivational salience of conditioned stimulus. Behavioural Pharmacology, 20: 84-98.

7. Sun, T, Hu, G, Li, M* (2008): Repeated antipsychotic treatment progressively potentiates inhibition on phencyclidine-induced hyperlocomotion, but attenuates inhibition on amphetamine-induced hyperlocomotion: Relevance to animal models of antipsychotic drugs: European Journal of Pharmacology

8. Zhao, CJ, Li, M* (2008): Sedation and disruption of maternal motivation underlie the disruptive effects of antipsychotic treatment on rat maternal behavior: Pharmacology, Biochemistry and Behavior.

9. Mead, A, Li, M*, Kapur, S (2008): Clozapine and Olanzapine Exhibit an Intrinsic Anxiolytic Property in Two Conditioned Fear Paradigms: Contrast with Haloperidol and Chlordiazepoxide, Pharmacology, Biochemistry and Behavior, 90 (2008) 551–562

10. Li, M*, He, W and Munro, R (2008): Amphetamine Selectively Enhances Avoidance Responding to a Less Salient Stimulus in Rats, Journal of Neural Transmission, 2008 May;115(5):773-6.

11. Parada, M, King, S, Li, M and Fleming, A (2008): The roles of accumbal dopamine D1 and D2 receptors in maternal memory in rats, Behavioral Neuroscience, Apr;122(2):368-76.

12. Li, M, Fletcher PJ, Kapur S (2007) Time Course of the Antipsychotic Effect and the Underlying Behavioral Mechanisms. Neuropsychopharmacology, 2007, Feb;32(2):263-72.

13. Smith AJ, Li, M, Becker S, Kapur S (2007) Linking Animal Models of Psychosis to Computational Models of Dopamine Function. Neuropsychopharmacology, 2007 Jan;32(1):54-66

14. Smith A, Li, M, Becker S, Kapur S (2006) Dopamine, prediction error and associative learning: A model-based account. Network 17:61-84.

15. Kapur, S, Agid, O, Mizrahi, R, and Li, M (2006) How antipsychotics work—From receptors to reality, NeuroRx, 3 (1), 10-21.

16. Li, M, Budin, R, Fleming, A, and Kapur, S (2005) Effects of novel antipsychotics, amisulpiride and aripiprazole, on maternal behavior in rats, Psychopharmacology (Berl). 2005, 181(3) 600-10.

17. Kapur, S, Mizrahi, R, and Li, M (2005) From dopamine to salience to psychosis - Linking biology, pharmacology and phenomenology of psychosis, Schizophrenia Research, 2005 Nov 1;79(1):59-68.

18. Li, M, Budin, R, Fleming, A, and Kapur, S (2005) Effects of chronic typical and atypical antipsychotic drug treatment on maternal behavior in rats, Schizophrenia Research, 75/2-3 pp 325-336.

19. Li, M, Parkes, J, Fletcher, PJ, and Kapur, S. (2004) Evaluation of the motor initiation hypothesis of APD-induced conditioned avoidance decreases, Pharmacology, Biochemistry and Behavior, 78(4), 811-819.

20. Smith, A, Li, M, Becker, S and Kapur, S. (2004) A Model of Antipsychotic Action in Conditioned Avoidance: A Computational Approach, Neuropsychopharmacology, 2004 Jun, 29(6) 1040-9.

21. Li, M, Davidson, P, Budin, R, Kapur, S and Fleming, A (2004) Effects of typical and atypical antipsychotic drugs on maternal behavior in postpartum female rats, Schizophrenia Research, 2004 Sep 1;70(1):69-80.

22. Li, M and A.S. Fleming (2003) The nucleus accumbens shell is critical for normal expression of pup-retrieval in postpartum female rats. Behavioural Brain Research, 2003. 145(1-2): p. 99-111.

23. Li, M and A.S. Fleming (2003) Differential involvement of nucleus accumbens shell and core subregions in maternal memory in postpartum female rats. Behavioral Neuroscience, 2003. 117(3): p. 426-45.

24. Lee, A., Li, M, Watchus, J, Fleming AS (1999) Neuroanatomical basis of maternal memory in postpartum rats: selective role for the nucleus accumbens. Behavioral Neuroscience, 1999. 113(3): p. 523-38.

Books Or Chapters Published

1. Fleming, A, and Li, M (2002). Psychobiology of maternal behavior in non-human mammals. Handbook of Parenting (second edition, eds. Marc H. Bornstein), Mahwah, N.J.: Lawrence Erlbaum Associates, 2002.

Research Funding Sources

Extramural Funding

1. National Alliance for Research on Schizophrenia and Depression (NARSAD) Young Investigator Award (July 2007-June 2009): Behavioral Mechanisms of Action of Atypical Antipsychotics: A Preclinical Investigation

2. Stanley Medical Research Institute Research Grant (Co-PI: Dr. Gang Hu, August 2007-July 2009): Iptakalim: A Potential Antipsychotic Drug with Novel Mechanisms

3. National Institute of Mental Health (NIMH) (September 2007-July 2010), Antipsychotic Drugs and Maternal Behavior: A Preclinical Investigation

4. National Institute of Mental Health (NIMH) (01/01/2008-12/31/2010), Anxiolytic Property of Atypical Antipsychotics

Intramural Funding

1. University of Nebraska-Lincoln Faculty Seed Grant (01/01/2008-12/31/2008): Characterizing Reconsolidation of Persistent Avoidance Responding